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How hormones work

mandchild

 

 

  Ovarian stimulation  
FSH and LH are secreted from the pituitary gland ovaries The follicles grow and produce estradiol. The ovary is stimulated to produce an oocyte.


The oocyte is released from the follicle to the fallopian tube.
                                                       Ovary       Fallopian tube  

 

The “suppression” drug stops the secretion of the LH hormone which is produced from the pituitary gland in the brain and causes ovulation.  In this way it’s possible to accurately regulate the time of ovulation.
The stimulation drug includes similar hormones to the ones that are secreted from the pituitary gland in order to stimulate the ovaries to produce follicles. The increase dosage of these hormones leads to the development of multiple follicles instead of single oocyte that matures in the natural cycle.

 

  IVF cycle  

The women’s own FSH and LH are not secreted from the pituitary gland – they are blocked by the antagonists   

FSH/LH injections stimulate the ovary  to develop multiple follicles

 

 

ovary-ivf

 

The follicles grow and produce estradiol


 The oocytes  are collected and are  fertilized in the IVF laboratory

     

 

The ovarian response is monitored by ultra-sound scan and blood tests of E2 (estradiol). For the final oocyte maturation a HCG injection is given 36 hours before the programmed egg collection  (similar to the  naturally occurring   LH hormone, which is secreted in the middle of cycle that triggers ovulation).

 

 

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